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Allysta Pharmaceuticals

Every Boy Deserves To Live A Normal, Healthy Life

About this Event

Duchenne Muscular Dystrophy (DMD) is a devastating genetic disease of boys in which relentless muscle damage due to a genetic defect results in progressive muscle cell injury, inflammation and loss of muscle function starting in early childhood. It is a billion-dollar market with few effective treatments and DMD subjects succumb to the disease in their twenties due to loss of heart and lung muscle function.

Allysta Pharmaceuticals Inc. is developinng as a completely novel treatment for DMD. Rather than targeting a single aspect of the disease, ALY688ER potentially improves all the key features of DMD that drive disease progression. Preclinical tests have produced substantial data showing the treatment reduced muscle cell death, enhanced muscle regeneration, and reduced inflammation and fibrosis. They have observed improvement in muscle function, including strength and endurance. This suggests the ability of ALY688ER to alter the trajectory of the disease, potentially allowing boys to maintain muscle function and quality of life.

ALY688, a synthesized peptide, is potent and specific activator of adiponectin signaling pathways. It is straightforward to produce, protected by issued patents, and has been shown to be safe and well tolerated in extensive toxicology studies. Due to its broad actions, it can be used to treat a myriad of inflammatory and fibrotic conditions, making it a single drug with multiple targets in the pipeline.

ALY688 has received Orphan Drug Designation for DMD from the FDA and is ready to begin Phase 1 clinical trials.

Register now to watch this webinar with Allysta Pharmaceutical CEO, Dr. Henry Hsu to learn how their first-in-class therapy improves in muscle function allowing boys to maintain muscle function and improve quality of life.

Hosted by Steven Saltzstein. CEO, Force Family Office

Video On Demand

– Recorded

May 2


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